| Weight | 351.446 g/mol |
|---|---|
| Formula | C22H25NO3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
Tamibarotene (94497-51-5)
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- Sigma-Aldrich - Tamibarotene74.30 - 287.50 USD
- Fisher Scientific - Search for Tamibarotene
- TCI - Search for Tamibarotene
- Tamibarotene: A Candidate Retinoid Drug for Alzheimers Disease (Biological & Pharmaceutical Bulletin, 2012)
- A Synthetic Retinoid Am80 (Tamibarotene) Rescues the Memory Deficit Caused by Scopolamine in a Passive Avoidance Paradigm (Biological & Pharmaceutical Bulletin, 2004)
- Oral Administration of Synthetic Retinoid Am80 (Tamibarotene) Decreases Brain -Amyloid Peptides in APP23 Mice (Biological & Pharmaceutical Bulletin, 2009)
- Antimyeloma effects of a novel synthetic retinoid Am80 (Tamibarotene) through inhibition of angiogenesis (Leukemia, 2005)
- All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C- (Journal of Leukocyte Biology, 2011)
- Synthesis and Pharmacological Characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, Silicon Analogues of the RAR-Selective Retinoid Agonists AM80 (Tamibarotene) and AM580 (ChemMedChem, 2009)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C
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- Pubchem - Tamibarotene
- Wikipedia - tamibarotene
Tamibarotene (brand name: Amnolake), also called retinobenzoic acid, is orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity against acute promyelocytic leukaemia (APL) . It is currently marketed only in Japan and early trials have demonstrated that it tends to be better tolerated than ATRA. It has also been investigated as a possible treatment for Alzheimer's disease, multiple myeloma and Crohn's disease.
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Tamibarotene
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