| Weight | 290.323 g/mol |
|---|---|
| Formula | C14H18N4O3 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Trimethoprim (738-70-5)
Proloprim · Trimpex
Score:
#23 in Microbiology
,
#510 in Biology
,
#538 in Chemistry
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LabBot
- Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system (Proteins, 1988)
- Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis (The New England Journal of Medicine, 1996)
- Adverse Reactions to Trimethoprim-Sulfamethoxazole in Patients with the Acquired Immunodeficiency Syndrome (Annals of Internal Medicine, 1984)
- Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment (Environmental Science & Technology, 2005)
- Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies (Science of The Total Environment, 2007)
- Efficacy of trimethoprim-sulphamethoxazole prophylaxis to decrease morbidity and mortality in HIV-1-infected patients with tuberculosis in Abidjan, Cte d'Ivoire: a randomised controlled trial (The Lancet, 1999)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Proloprim
- Trimpex
-
SMILESCOC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
-
InChIKeyIEDVJHCEMCRBQM-UHFFFAOYSA-N
- Pubchem - Trimethoprim
- Wikipedia - trimethoprim
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers' diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.
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Alternate Names
Estimated Properties
| Boiling Point | 406.38 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.34 g/cm3 | EPA T.E.S.T. |
| Flash Point | 263.07 C | EPA T.E.S.T. |
| Water Solubility | 263.17 mg/L | EPA T.E.S.T. |
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Trimethoprim
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