| Weight | 129.159 g/mol |
|---|---|
| Formula | C6H11NO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
vigabatrin (68506-86-5, 60643-86-9)
Sabril · gamma-Vinyl-gamma-Aminobutyric Acid · gamma-Vinyl-GABA
Score:
#115 in Neurology
,
#542 in Neuroscience
,
#2461 in Biology
,
#3067 in Chemistry
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- Sigma-Aldrich - vigabatrin85.50 - 485.10 USD
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- Severe persistent visual field constriction associated with vigabatrin (BMJ, 1997)
- Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control. (Drugs, 1991)
- Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis (Epilepsy Research, 1997)
- Vigabatrin-associated retinal cone system dysfunction Electroretinogram and ophthalmologic findings (Neurology, 1998)
- The United Kingdom Infantile Spasms Study (UKISS) comparing hormone treatment with vigabatrin on developmental and epilepsy outcomes to age 14 months: a multicentre randomised trial (Lancet Neurology, 2005)
- The United Kingdom Infantile Spasms Study comparing vigabatrin with prednisolone or tetracosactide at 14 days: a multicentre, randomised controlled trial (The Lancet, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Sabril
- gamma-Vinyl-gamma-Aminobutyric Acid
- gamma-Vinyl-GABA
- gamma Vinyl gamma Aminobutyric Acid
- Sabrilex
- gamma Vinyl GABA
-
SMILESC=CC(CCC(=O)O)N
-
InChIKeyPJDFLNIOAUIZSL-UHFFFAOYSA-N
- Pubchem - vigabatrin
- Wikipedia - vigabatrin
Vigabatrin, brand name Sabril, is an antiepileptic drug that inhibits the breakdown of -aminobutyric acid (GABA) by acting as a suicide inhibitor of the enzyme GABA transaminase (GABA-T). It is also known as -vinyl-GABA, and is a structural analogue of GABA, but does not bind to GABA receptors.
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vigabatrin
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