| Weight | 83.134 g/mol |
|---|---|
| Formula | C5H9N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
1,2,3,6-Tetrahydropyridine (694-05-3)
Score:
#863 in Neuroscience
,
#3778 in Biology
,
#4757 in Chemistry
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- A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (Proceedings of the National Academy of Sciences of the United States of America, 1983)
- Mice Deficient in Cellular Glutathione Peroxidase Show Increased Vulnerability to Malonate, 3-Nitropropionic Acid, and 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine (The Journal of Neuroscience, 2000)
- Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. (Proceedings of the National Academy of Sciences of the United States of America, 1985)
- Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease (The Journal of Neuroscience, 2002)
- Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. (Annals of Neurology, 1999)
- Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity (Proceedings of the National Academy of Sciences of the United States of America, 1996)
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SMILESC1CNCC=C1
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InChIKeyFTAHXMZRJCZXDL-UHFFFAOYSA-N
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1,2,3,6-Tetrahydropyridine
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