Norspermidine (56-18-8)

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Suppliers

• Sigma-Aldrich - Norspermidine
  42.30 - 108.50 USD
• Fisher Scientific - Search for Norspermidine
• TCI - Norspermidine
  23.00 - 87.00 USD

Most-cited Publications

• NspS, a Predicted Polyamine Sensor, Mediates Activation of Vibrio cholerae Biofilm Formation by Norspermidine (Journal of Bacteriology, 2005)
• Widespread occurrence of norspermidine and norspermine in eukaryotic algae. (Journal of Biochemistry, 1982)
• Polyamine distribution in Vibrionaceae: norspermidine as a general constituent of Vibrio species (Canadian Journal of Microbiology, 1983)
• Detection of Norspermidine and Norspermine in Medicago sativa L. (Alfalfa) (Plant Physiology, 1989)
• Membrane Active Phenylalanine Conjugated Lipophilic Norspermidine Derivatives with Selective Antibacterial Activity (Journal of Medicinal Chemistry, 2014)
• Norspermidine Is Not a Self-Produced Trigger for Biofilm Disassembly (Cell, 2014)

Areas of Application

Safety

• Request a Demo
  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
• H227: Combustible liquid
  Warning Flammable liquids - Category 4
• H302: Harmful if swallowed
  Warning Acute toxicity, oral - Category 4
• H314: Causes severe skin burns and eye damage
  Danger Skin corrosion/irritation - Category 1A, B, C
• H318: Causes serious eye damage
  Danger Serious eye damage/eye irritation - Category 1
• H330: Fatal if inhaled
  Danger Acute toxicity, inhalation - Category 1, 2

Trends

Alternate Names

• 3,3'-iminobispropylamine
• bis(3,3'-aminopropyl)amine
• 3,3'-diaminopropylamine
• SMILES
  C(CN)CNCCCN
• InChIKey
  OTBHHUPVCYLGQO-UHFFFAOYSA-N

External Links

• Pubchem - Norspermidine
• Wikipedia - dipropylenetriamine
  Norspermidine is a polyamine of similar structure to the more common spermidine. While norspermidine has been found to occur naturally in some species of plants, bacteria, and algae, it is not known to exist in humans. Norspermidine is being researched for use as a cancer medication.

Synthesis

1,3-diaminopropane  +  3-chloropropan-1-amine (Alkylation of primary amines)

Synthesis of Norspermidine ›

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Norspermidine

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