Weight | 133.194 g/mol |
---|---|
Formula | C9H11N |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
1-Aminoindan (61949-83-5, 34698-41-4)
Score:
#1182 in Neuroscience
,
#5098 in Biology
,
#6610 in Chemistry
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- Pharmacological Characterization of 1-Aminoindan-1,5-dicarboxylic Acid, a Potent mGluR1 Antagonist (Journal of Pharmacology and Experimental Therapeutics, 1997)
- 1-aminoindan-1,5-dicarboxylic acid : a novel antagonist at phospholipase C-linked metabotropic glutamate receptors (Journal of Medicinal Chemistry, 1995)
- Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan (Journal of Neurochemistry, 2002)
- 1Aminoindan1,5dicarboxylic acid and (S)(+)2(3carboxybicyclo[1.1.1] pentyl)glycine, two mGlu1 receptorpreferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia (European Journal of Neuroscience, 1999)
- N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-B transcription factor (Neurochemistry International, 2004)
- An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic Bcl-2 in human dopaminergic SH-SY5Y cells (Neuroscience Letters, 2002)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CC2=CC=CC=C2C1N
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InChIKeyXJEVHMGJSYVQBQ-UHFFFAOYSA-N
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