Weight | 136.114 g/mol |
---|---|
Formula | C5H4N4O |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 0 |
1-Hydroxy-7-azabenzotriazole (39968-33-7)
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- 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive (Journal of the American Chemical Society, 1993)
- Efficiency in Peptide Coupling: 1-Hydroxy-7-azabenzotriazole vs 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine (Journal of Organic Chemistry, 1995)
- The diisopropylcarbodiimide/ 1-hydroxy-7-azabenzotriazole system: Segment coupling and stepwise peptide assembly (Tetrahedron, 1999)
- CYCLIZATION OF ALL-L-PENTAPEPTIDES BY MEANS OF 1-HYDROXY-7-AZABENZOTRIAZOLE-DERIVED URONIUM AND PHOSPHONIUM REAGENTS (Journal of Organic Chemistry, 1996)
- Organophosphorus and nitro-substituted sulfonate esters of 1-hydroxy-7-azabenzotriazole as highly efficient fast-acting peptide coupling reagents. (Journal of Organic Chemistry, 2004)
- The 5,6- and 4,5-benzo derivatives of 1-hydroxy-7-azabenzotriazole. (Organic Letters, 2001)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC2=C(N=C1)N(N=N2)O
-
InChIKeyFPIRBHDGWMWJEP-UHFFFAOYSA-N
- Pubchem - 1-Hydroxy-7-azabenzotriazole
- Wikipedia - 1-hydroxy-7-azabenzotriazole
1-Hydroxy-7-azabenzotriazole, commonly abbreviated HOAt, is a triazole used as a peptide coupling reagent. It suppresses the loss of chirality.
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