| Weight | 442.285 g/mol |
|---|---|
| Formula | C12H22F6N6OP2 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
56602-33-6 (56602-33-6)
BOP reagent · benzotriazol-1-yloxy-tris(dimethylamino)phosphonium · BTZO-TDMAP
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- Applications of BOP reagent in solid phase synthesis. II: Solid phase side-chain to side-chain cyclizations using BOP reagent (International Journal of Peptide and Protein Research, 2009)
- Applications of BOP reagent in solid phase synthesis Advantages of BOP reagent for difficult couplings exemplified by a synthesis of [Ala 15]-GRF(129)-NH2 (International Journal of Peptide and Protein Research, 2009)
- Peptide Coupling Reagents VI1. A Novel, Cheaper Preparation of Benzotriazolyloxytris[dimethylamino]phosphonium Hexafluorophosphate (BOP Reagent) (Synthesis, 1976)
- N,N'bis(2oxo3oxazolidinyl) phosphinic chloride (BOPCl); a superb reagent for coupling at and with iminoacid residues (International Journal of Peptide and Protein Research, 2009)
- FACILE AND CHEMOSELECTIVE REDUCTION OF CARBOXYLIC ACIDS TO ALCOHOLS USING BOP REAGENT AND SODIUM BOROHYDRIDE (Tetrahedron Letters, 1998)
- BOP as a reagent for mild and efficient preparation of esters (Tetrahedron Letters, 1994)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - BOP reagent
- benzotriazol-1-yloxy-tris(dimethylamino)phosphonium
- BTZO-TDMAP
- benzotriazol-1-yloxy-tris(dimethylamino)phosphonium tetrafluoroborate
- benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate
-
SMILESCN(C)[P+](N(C)C)(N(C)C)ON1C2=CC=CC=C2N=N1.F[P-](F)(F)(F)(F)F
-
InChIKeyMGEVGECQZUIPSV-UHFFFAOYSA-N
- Pubchem - 56602-33-6
- Wikipedia - BOP reagent
BOP reagent is a reagent commonly used in the synthesis of peptides. Its use is discouraged because coupling using BOP liberates HMPA which is carcinogenic, although for small scale use in an organic laboratory this is not a great disadvantage as it is in large scale industrial usage.
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