Weight | 393.355 g/mol |
---|---|
Formula | C20H15N3O6 |
Hydrogen Acceptors | 8 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 2 |
Rubitecan (91421-42-0)
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- Sigma-Aldrich - Rubitecan37.90 - 148.00 USD
- Fisher Scientific - Search for Rubitecan
- TCI - Rubitecan281.00 USD
- Phase II Trial of Oral Rubitecan in Previously Treated Pancreatic Cancer Patients (Oncologist, 2005)
- Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan). (International Journal of Oncology, 2002)
- Clinical phase II study and pharmacological evaluation of rubitecan in non-pretreated patients with metastatic colorectal cancer-significant effect of food intake on the bioavailability of the oral camptothecin analogue. (European Journal of Cancer, 2002)
- A randomized phase III study of rubitecan (ORA) vs. best choice (BC) in 409 patients with refractory pancreatic cancer report from a North-American multi-center study (Journal of Clinical Oncology, 2004)
- Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule (Cancer Chemotherapy and Pharmacology, 2002)
- A phase II trial with RFS2000 (rubitecan) in patients with advanced non-small cell lung cancer. (European Journal of Cancer, 2005)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)[N+](=O)[O-])O
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- Pubchem - Rubitecan
- Wikipedia - Rubitecan
Rubitecan (INN, marketing name Orathecin) is an oral topoisomerase inhibitor, developed by Supergen.
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