| Weight | 144.177 g/mol |
|---|---|
| Formula | C9H8N2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
4-Aminoquinoline (578-68-7)
Score:
#37 in Medicinal chemistry
,
#2532 in Biochemistry
,
#4924 in Biology
,
#6310 in Chemistry
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- 4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum. (Antimicrobial Agents and Chemotherapy, 1996)
- StructureActivity Relationships in 4-Aminoquinoline Antiplasmodials. The Role of the Group at the 7-Position (Journal of Medicinal Chemistry, 2002)
- STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. VI. THE PHYSIOLOGICAL DISPOSITION, ANTIMALARIAL ACTIVITY, AND TOXICITY OF SEVERAL DERIVATIVES OF 4-AMINOQUINOLINE (Journal of Clinical Investigation, 1948)
- Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives. (Bioorganic & Medicinal Chemistry, 2005)
- Synthesis and Antimalarial Activity of Side Chain Modified 4-Aminoquinoline Derivatives (Journal of Medicinal Chemistry, 2007)
- Preparation and Antimalarial Activities of Trioxaquines, New Modular Molecules with a Trioxane Skeleton Linked to a 4Aminoquinoline (ChemBioChem, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC=C2C(=C1)C(=CC=N2)N
-
InChIKeyFQYRLEXKXQRZDH-UHFFFAOYSA-N
- Pubchem - 4-Aminoquinoline
- Wikipedia - 4-aminoquinoline
4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline. A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine.
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