Weight | 190.158 g/mol |
---|---|
Formula | C9H6N2O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 1 |
4-Nitroquinoline N-oxide (56-57-5)
4-Nitroquinoline-N-oxide · 4 Nitroquinoline N oxide · 4 Nitroquinoline 1 oxide
Score:
#209 in Microbiology
,
#750 in Biochemistry
,
#2074 in Biology
,
#2540 in Chemistry
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- Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases (Molecular Genetics and Genomics, 1993)
- Effects in rats of sodium chloride on experimental gastric cancers induced by N-methyl-N-nitro-N-nitrosoguanidine or 4-nitroquinoline-1-oxide. (Journal of the National Cancer Institute, 1975)
- Carcinogenic action of 4-nitroquinoline-N-oxide. (1957)
- Potent Intracellular Oxidative Stress Exerted by the Carcinogen 4-Nitroquinoline-N-oxide (Cancer Research, 1993)
- Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. (The FASEB Journal, 2002)
- Role of the ABC transporter TruMDR2 in terbinafine, 4-nitroquinoline N-oxide and ethidium bromide susceptibility in Trichophyton rubrum (Journal of Medical Microbiology, 2006)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 4-Nitroquinoline-N-oxide
- 4 Nitroquinoline N oxide
- 4 Nitroquinoline 1 oxide
- 4-Nitroquinoline-1-oxide
-
SMILESC1=CC=C2C(=C1)C(=CC=[N+]2[O-])[N+](=O)[O-]
-
InChIKeyYHQDZJICGQWFHK-UHFFFAOYSA-N
- Pubchem - 4-Nitroquinoline N-oxide
- Wikipedia - 4-nitroquinoline-N-oxide
4-Nitroquinoline 1-oxide (also known as 4-NQO, 4NQO, 4Nqo, NQO and NQNO) is a quinoline derivative and a tumorigenic compound used in the assessment of the efficacy of diets, drugs, and procedures in the prevention and treatment of cancer in animal models. It induces DNA lesions usually corrected by nucleotide excision repair.
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