| Weight | 152.584 g/mol |
|---|---|
| Formula | C7H5ClN2 |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
5-Chloro-1H-indazole (698-26-0)
698-26-0
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- Inhibition of neuronal nitric oxide synthase activity by 3-[2-[4-(3-chloro-2-methylphenyl)- 1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel neuroprotective agent, in vitro and in cultured neuroblastoma cells in situ (Biochemical Pharmacology, 2000)
- The neuroprotective effect of a novel calmodulin antagonist, 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate, in transient forebrain ischemia. (Neuroscience, 2003)
- 3-[2-[4-(3-Chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydro-chloride 3.5 Hydrate (DY-9760e) Is Neuroprotective in Rat Microsphere Embolism: Role of the Cross-Talk between Calpain and Caspase-3 through Calpastatin (Journal of Pharmacology and Experimental Therapeutics, 2006)
- 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e), a Novel Calmodulin Antagonist, Reduces Brain Edema through the Inhibition of Enhanced Blood-Brain Barrier Permeability after Transient Focal Ischemia (Journal of Pharmacology and Experimental Therapeutics, 2002)
- Synthesis and biological evaluation of 5-arylamino-6-chloro-1H-indazole-4,7-diones as inhibitors of protein kinase B/Akt. (Bioorganic & Medicinal Chemistry Letters, 2006)
- Inhibition of Dystrophin Breakdown and Endothelial Nitric-Oxide Synthase Uncoupling Accounts for Cytoprotection by 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) in Left Ventricular Hypertrophied Mice (Journal of Pharmacology and Experimental Therapeutics, 2010)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 698-26-0
-
SMILESC1=CC2=C(C=C1Cl)C=NN2
-
InChIKeyFVNCILPDWNBPLK-UHFFFAOYSA-N
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Alternate Names
Estimated Properties
| Boiling Point | 317.68 C | EPA T.E.S.T. |
|---|---|---|
| Boiling Point | 310.76 C | EPI Suite |
| Density | 1.43 g/cm3 | EPA T.E.S.T. |
| Flash Point | 142.74 C | EPA T.E.S.T. |
| Melting Point | 92.95 C | EPI Suite |
| Water Solubility | 1707.44 mg/L | EPA T.E.S.T. |
| Water Solubility | 1082.9 mg/L | EPI Suite |
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