716-61-0 (716-61-0, 3689-55-2)

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Suppliers

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  5 g
  $27.00

  25 g
  $93.00

  100 g
  $261.00

  5 g
  $26.00

  25 g
  $103.00

Most-cited Publications

• Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate. (Biochemistry, 1994)
• Studies on Optically Active Amino Acids. IV. A New Synthetic Approach to Chloramphenicol Base from L-Phenylalanine. (Chemical & Pharmaceutical Bulletin, 1963)
• Pharmacokinetic, residue and irritation aspects of chloramphenicol sodium succinate and a chloramphenicol base formulation following intramuscular administration to ruminants (Veterinary Quarterly, 1986)
• A new cost-effective Ru-chloramphenicol base derivative catalyst for the asymmetric transfer hydrogenation/dynamic kinetic resolution of N-Boc -amino--ketoesters and its application to the synthesis of the chiral core of vancomycin (RSC Advances, 2016)
• Development of Bifunctional Thiourea Organocatalysts Derived from a Chloramphenicol Base Scaffold and their Use in the Enantioselective Alcoholysis of meso Cyclic Anhydrides (Chemcatchem, 2016)
• New chloramphenicol Schiff base ligands for the titanium-mediated asymmetric aldol reaction of ,-unsaturated aldehydes with diketene: a short synthesis of atorvastatin calcium (RSC Advances, 2016)

Safety

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Trends

Alternate Names

• chloramphenicol base
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, mono-hydrochloride, (1R,2R)-isomer
• 1-(4-nitrophenyl)-1,3-dihydroxypropylamine
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, (S-(R*,R*))-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, mononitrate
• 2-amino-1-nitrophenylpropane-1,3-diol
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol mono-hydrochloride, (S-(R*,R*))-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, mono-HCl(R*,R*)-(+-)-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, (R-(R*,S*))-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, (R-(R*,R*))-isomer
• para-nitrophenylserinal
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, (R*,S*)-(+-)-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, (R*,R*)-(+-)-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, (S)-hydroxybutanedioate (2:1) (S-(R*,R*))-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, mono-L-(+)-tartrate(R-(R*,R*))-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, L-(+)-tartrate(S-(R*,R*))-isomer
• 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol, sulfate(S-(R*,R*))-isomer
• SMILES
  C1=CC(=CC=C1C(C(CO)N)O)[N+](=O)[O-]
• InChIKey
  OCYJXSUPZMNXEN-UHFFFAOYSA-N

External Links

• Pubchem - 716-61-0
• Wikipedia - (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol

Synthesis

AC1MHERO  +  4-Chloronitrobenzene (Grignard alcohol)

Synthesis of 716-61-0 ›

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