| Weight | 400.488 g/mol |
|---|---|
| Formula | C10H20CaN2O8S2 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 8 |
Acamprosate calcium (77337-73-6)
AOTA · acamprosate · Campral
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- Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review (Addiction, 2004)
- Relapse Prevention by Acamprosate: Results From a Placebo-Controlled Study on Alcohol Dependence (Archives of General Psychiatry, 1996)
- Efficacy of Naltrexone and Acamprosate for Alcoholism Treatment: A Meta-Analysis (Alcoholism: Clinical and Experimental Research, 2001)
- Comparing and Combining Naltrexone and Acamprosate in Relapse Prevention of Alcoholism A Double-blind, Placebo-Controlled Study (Archives of General Psychiatry, 2003)
- The efficacy of acamprosate in the maintenance of abstinence in alcohol-dependent individuals: Results of a meta-analysis (Alcoholism: Clinical and Experimental Research, 2004)
- Comparison of acamprosate and placebo in long-term treatment of alcohol dependence (The Lancet, 1996)
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- acamprosate
- Campral
- calcium acetylhomotaurinate
- N-acetylhomotaurine, monopotassium salt
- Zulex
- N-acetylhomotaurine, magnesium (2:1) salt
- N-acetylhomotaurine, monolithium salt
- calcium acetylhomotaurine
- N-acetylhomotaurine, zinc (2:1) salt
- calcium acetyl homotaurinate
- N-acetylhomotaurine
- Campral EC
- sodium acetylhomotaurine
- N-acetylhomotaurine, calcium (2:1) salt
- Regtect
- Aotal
- acamprostate
- N-acetylhomotaurine, monosodium salt
-
SMILESCC(=O)NCCCS(=O)(=O)[O-].CC(=O)NCCCS(=O)(=O)[O-].[Ca+2]
-
InChIKeyBUVGWDNTAWHSKI-UHFFFAOYSA-L
- Pubchem - Acamprosate calcium
- Wikipedia - acamprosate calcium
Acamprosate, sold under the brand name Campral, is a medication used along with counselling to treat alcohol dependence. Acamprosate is thought to stabilize chemical signaling in the brain that would otherwise be disrupted by alcohol withdrawal. When used alone, acamprosate is not an effective therapy for alcoholism in most individuals; however, studies have found that acamprosate works best when used in combination with psychosocial support since it facilitates a reduction in alcohol consumption as well as full abstinence.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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Acamprosate calcium
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