| Weight | 336.432 g/mol |
|---|---|
| Formula | C18H28N2O4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 10 |
acebutolol (37517-30-9)
Prent · Sectral · Acebutolol Hydrochloride
Score:
#307 in Neuroscience
,
#1374 in Biology
,
#1609 in Chemistry
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- Acebutolol, atenolol, and propranolol and metabolic responses to acute hypoglycaemia in diabetics. (BMJ, 1977)
- Secondary prevention after high-risk acute myocardial infarction with low-dose acebutolol (American Journal of Cardiology, 1990)
- Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone. (Thorax, 1989)
- Potential for biodegradation and sorption of acetaminophen, caffeine, propranolol and acebutolol in lab-scale aqueous environments (Journal of Hazardous Materials, 2010)
- Prevention of atrial fibrillation or flutter by acebutolol after coronary bypass grafting (American Journal of Cardiology, 1986)
- Blockade of isoprenalineinduced changes in plasma free fatty acids, immunoreactive insulin levels and plasma renin activity in healthy human subjects, by propranolol, pindolol, practolol, atenolol, metoprolol and acebutolol. (British Journal of Clinical Pharmacology, 1978)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Prent
- Sectral
- Acebutolol Hydrochloride
- Monitan
- Rhotral
- M and B17803 A
- M and B 17803 A
- Apo Acebutolol
- M and B-17803 A
- Novo-Acebutolol
- Novo Acebutolol
- M and B 17803A
- Apo-Acebutolol
- NovoAcebutolol
- Neptal
- ApoAcebutolol
- Acetobutolol
-
SMILESCCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C
-
InChIKeyGOEMGAFJFRBGGG-UHFFFAOYSA-N
- Pubchem - acebutolol
- Wikipedia - acebutolol
Acebutolol (trade names Sectral, Prent) is a beta blocker for the treatment of hypertension and arrhythmias.
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Synthesis
ISOPROPYLAMINE
+
Reactant
(Alkylation of primary amines)
40188-45-2
+
Reactant
(Williamson ether)
Acetonitrile
+
Reactant
(Grignard carbonyl)
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acebutolol
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