Weight | 273.189 g/mol |
---|---|
Formula | C8H12N5O4P |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 3 |
Aromatic Rings | 2 |
Rotatable Bonds | 5 |
ADEFOVIR (106941-25-7)
Score:
#159 in Microbiology
,
#1697 in Biology
,
#1998 in Chemistry
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- Adefovir Dipivoxil for the Treatment of Hepatitis B e AntigenPositive Chronic Hepatitis B (The New England Journal of Medicine, 2003)
- Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B (The New England Journal of Medicine, 2003)
- Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for Chronic Hepatitis B (The New England Journal of Medicine, 2008)
- Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years (Gastroenterology, 2006)
- Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. (Gastroenterology, 2004)
- Resistance to Adefovir Dipivoxil Therapy Associated With the Selection of a Novel Mutation in the HBV Polymerase (Gastroenterology, 2003)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=NC2=C(C(=N1)N)N=CN2CCOCP(=O)(O)O
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InChIKeySUPKOOSCJHTBAH-UHFFFAOYSA-N
- Pubchem - ADEFOVIR
- Wikipedia - adefovir
Adefovir is a prescription medicine used to treat (chronic) infections with hepatitis B virus. A prodrug form of adefovir was previously called bis-POM PMEA, with trade names Preveon and Hepsera. It is an orally administered nucleotide analog reverse transcriptase inhibitor (ntRTI).
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