ALVERINE CITRATE (5560-59-8)

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  5 g
  $125.00

Most-cited Publications

• Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome a randomized, doubleblind, placebocontrolled study (Alimentary Pharmacology & Therapeutics, 2010)
• Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype (Journal of Pharmacy and Pharmacology, 2001)
• Alverine citrate fails to relieve the symptoms of irritable bowel syndrome: results of a double-blind, randomized, placebo-controlled trial (Alimentary Pharmacology & Therapeutics, 2002)
• Construction of 3-arylpropylamines using Heck arylations. The total synthesis of cinacalcet hydrochloride, alverine, and tolpropamine (Tetrahedron, 2014)
• Effects of alverine citrate on cat intestinal mechanoreceptor responses to chemical and mechanical stimuli (Alimentary Pharmacology & Therapeutics, 1999)
• Evolving mechanisms of action of alverine citrate on phasic smooth muscles. (British Journal of Pharmacology, 2007)

Safety

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Trends

Alternate Names

• alverine
• Norgine brand of alverine citrate
• alverine hydrochloride
• United Drug brand of alverine citrate
• Spasmonal
• Spasmaverine
• SMILES
  CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
• InChIKey
  RYHCACJBKCOBTJ-UHFFFAOYSA-N

External Links

• Pubchem - ALVERINE CITRATE
• Wikipedia - alverine citrate

Synthesis

3-phenylpropylboronic Acid  +  N-ethyl-3-phenylpropan-1-amine (Chan-Lam coupling reaction)

benzene  +  Reactant (Friedel-Crafts alkylation)

Synthesis of ALVERINE CITRATE ›

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ALVERINE CITRATE

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