| Weight | 240.306 g/mol |
|---|---|
| Formula | C15H16N2O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
Ameltolide (787-93-9)
4-amino-N-(2,6-dimethylphenyl)benzamide · 787-93-9
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- Fluoxetine, a Selective SerotoninUptake Inhibitor, Enhances the Anticonvulsant Effects of Phenytoin, Carbamazepine, and Ameltolide (LY 201116) (Epilepsia, 1992)
- Comparative Anticonvulsant Activity and Neurotoxicity of 4AminoN(2,6dimethylphenyl) benzamide and Prototype Antiepileptic Drugs in Mice and Rats (Epilepsia, 1988)
- Anticonvulsant activity and interactions with neuronal voltage-dependent sodium channel of analogues of ameltolide (Journal of Medicinal Chemistry, 1998)
- Metabolism, disposition, and pharmacokinetics of a potent anticonvulsant, 4-amino-N-(2,6-dimethylphenyl)benzamide (LY201116), in rats. (Drug Metabolism and Disposition, 1989)
- Anticonvulsant and neurotoxicological properties of 4-amino-N-(2-ethylphenyl)benzamide, a potent ameltolide analogue (Biomedicine & Pharmacotherapy, 1997)
- Synthesis and pharmacological evaluation of a major metabolite of ameltolide, a potent anticonvulsant (Journal of Medicinal Chemistry, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 4-amino-N-(2,6-dimethylphenyl)benzamide
- 787-93-9
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SMILESCC1=C(C(=CC=C1)C)NC(=O)C2=CC=C(C=C2)N
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InChIKeyHZIWGOAXOBPQGY-UHFFFAOYSA-N
- Pubchem - Ameltolide
- Wikipedia - ameltolide
Ameltolide, a 4-aminobenzamide derivative, is an experimental anticonvulsant agent, effective at inhibiting seizures in animal models. It is non-toxic at dosing levels and no undesirable side effects are attributable to its application.
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Safety
Alternate Names
Estimated Properties
| Boiling Point | 366.39 C | EPA T.E.S.T. |
|---|---|---|
| Boiling Point | 444.26 C | EPI Suite |
| Density | 1.19 g/cm3 | EPA T.E.S.T. |
| Flash Point | 194.19 C | EPA T.E.S.T. |
| Melting Point | 186.56 C | EPI Suite |
| Water Solubility | 34.76 mg/L | EPA T.E.S.T. |
| Water Solubility | 7.8688 mg/L | EPI Suite |
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Synthesis
Similar Compounds
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2-amino-N-(2,4-dimethylphenyl)benzamide
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3-amino-N-(2,3-dimethylphenyl)benzamide
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4-amino-N-(3,5-dimethylphenyl)benzamide
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4-Amino-N-phenylbenzamide
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4-amino-N-(4-methylphenyl)benzamide
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32212-38-7
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3-amino-N-(4-methylphenyl)benzamide
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N-(3-methylphenyl)benzamide
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N-(3-aminophenyl)-3-methylbenzamide
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2-(Benzoylamino)benzoic acid
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3-fluoro-N-(4-iodo-2-methylphenyl)benzamide
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4-bromo-N-phenylbenzamide
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N-(4-Bromophenyl)benzamide
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N-(3-aminophenyl)-4-methylbenzamide
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3-amino-N-(3,4-dimethylphenyl)benzamide
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Benzamide, N-[4-(1-methylethyl)phenyl]-
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4-ethoxy-N-(4-iodo-2-methylphenyl)benzamide
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2-amino-N-(3-methylphenyl)benzamide
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N-(4-acetylphenyl)-4-methylbenzamide
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4-amino-N-(3-chlorophenyl)benzamide
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N-(4-IODO-2-ISOPROPYLPHENYL)BENZAMIDE
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N-(3-cyanophenyl)benzamide
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4-amino-N-(4-methoxyphenyl)benzamide
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3-chloro-N-(4-methylphenyl)benzamide
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N-(3-aminophenyl)-4-chlorobenzamide
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4-amino-N-(3-methoxyphenyl)benzamide
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3-bromo-N-phenylbenzamide
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4-amino-N-(2-chlorophenyl)benzamide
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N-(4-acetylphenyl)-2-methylbenzamide
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2-amino-N-(3-chlorophenyl)benzamide
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2-iodo-N-(4-methylphenyl)benzamide
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N-(4-acetylphenyl)-4-chlorobenzamide
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3-(benzoylamino)benzoic acid
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N-(3-AMINOPHENYL)-4-METHOXYBENZAMIDE
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4'-Nitrobenzanilide
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3-amino-N-(4-fluorophenyl)benzamide
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N-(4-aminophenyl)-4-(tert-butyl)benzamide
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N-[3-(trifluoromethyl)phenyl]benzamide
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N-(2-amino-4-methylphenyl)-2-methylbenzamide
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N-(4-acetylphenyl)-4-methoxybenzamide
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3-Amino-N-(3-chlorophenyl)benzamide
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4-amino-n-pyridin-3-ylbenzamide
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2-amino-N-(4-ethoxyphenyl)benzamide
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N-(2-chlorophenyl)-3-methylbenzamide
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Ameltolide
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