| Weight | 91.066 g/mol |
|---|---|
| Formula | C2H5NO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
Aminooxyacetic acid (645-88-5, 2921-14-4)
Aminooxyacetate · Carboxymethoxyamine
Score:
#1141 in Neuroscience
,
#2545 in Biochemistry
,
#4944 in Biology
,
#6337 in Chemistry
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- Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain (Neuroscience Letters, 1991)
- Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: differences revealed using aminooxyacetate. (Developmental Neuroscience, 1993)
- Aminooxyacetic Acid Results in Excitotoxin Lesions by a Novel Indirect Mechanism (Journal of Neurochemistry, 1991)
- THE ROLE OF GABA METABOLISM IN THE CONVULSANT AND ANTICONVULSANT ACTIONS OF AMINOOXYACETIC ACID (Journal of Neurochemistry, 1973)
- Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons. (Epilepsy Research, 1988)
- 3-Mercaptopropionic acid: Convulsant properties, effects on enzymes of the -aminobutyrate system in mouse brain and antagonism by certain anticonvulsant drugs, aminooxyacetic acid and gabaculine (Biochemical Pharmacology, 1979)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Aminooxyacetate
- Carboxymethoxyamine
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SMILESC(C(=O)O)ON
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InChIKeyNQRKYASMKDDGHT-UHFFFAOYSA-N
- Pubchem - Aminooxyacetic acid
- Wikipedia - aminooxyacetic acid
Aminooxyacetic acid, often abbreviated AOA or AOAA, is a compound that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down. Subsequently, the level of GABA is increased in tissues. At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a useful tool to study regional GABA turnover in rats.
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