| Weight | 380.488 g/mol |
|---|---|
| Formula | C23H28N2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
BOPINDOLOL (62658-63-3, 69010-88-4)
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- Interindividual variation of beta-adrenoceptor blocking drugs, plasma concentration and effect: Influence of genetic status on behaviour of atenolol, bopindolol and metoprolol (European Journal of Clinical Pharmacology, 1985)
- Simultaneous modeling of bopindolol kinetics and dynamics (Clinical Pharmacology & Therapeutics, 1984)
- Certain beta-blockers can decrease beta-adrenergic receptor number: I. Acute reduction in receptor number by tertatolol and bopindolol. (Circulation Research, 1988)
- Pharmacological experiments in healthy volunteers with bopindolol, a long-acting beta-adrenoceptor blocking drug with partial agonist activity. (British Journal of Clinical Pharmacology, 1985)
- Effect of propranolol, alprenolol, pindolol, and bopindolol on beta 2-adrenoceptor density in human lymphocytes. (Journal of Cardiovascular Pharmacology, 1986)
- Effects of a new long-acting beta-blocker bopindolol (LT 31-200) on blood pressure, plasma catecholamines, renin and cholesterol in patients with arterial hypertension (European Journal of Clinical Pharmacology, 1982)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3
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InChIKeyUUOJIACWOAYWEZ-UHFFFAOYSA-N
- Pubchem - BOPINDOLOL
- Wikipedia - bopindolol
Bopindolol (INN) is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole.
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Synthesis
4-Hydroxy-2-methylindole
+
Reactant
(Williamson ether)
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