| Weight | 334.169 g/mol |
|---|---|
| Formula | C15H12BrNO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Bromfenac (120638-55-3, 91714-94-2)
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- A systematic review of NSAIDs withdrawn from the market due to hepatotoxicity: lessons learned from the bromfenac experience (Pharmacoepidemiology and Drug Safety, 2006)
- A new approach to the analysis of analgesic drug trials, illustrated with bromfenac data (Clinical Pharmacology & Therapeutics, 1994)
- In vivo pharmacokinetics and in vitro pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac (Journal of Cataract and Refractive Surgery, 2007)
- Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. (Current Medical Research and Opinion, 2006)
- Acute liver failure associated with prolonged use of bromfenac leading to liver transplantation (Liver Transplantation, 1999)
- Bromfenac Ophthalmic Solution 0.09% (Xibrom) for Postoperative Ocular Pain and Inflammation (Ophthalmology, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC(=C(C(=C1)CC(=O)O)N)C(=O)C2=CC=C(C=C2)Br
-
InChIKeyZBPLOVFIXSTCRZ-UHFFFAOYSA-N
- Pubchem - Bromfenac
- Wikipedia - bromfenac
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) marketed in the US as an ophthalmic solution (current brand names Prolensa and Bromday, prior formulation brand name Xibrom, which has since been discontinued) by ISTA Pharmaceuticals for short-term, local use. Prolensa and Bromday are the once-daily formulation of bromfenac, while Xibrom was approved for twice-daily administration. In Europe, the trade name is Yellox.
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Reactant
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1-Bromo-4-chlorobenzene
(Grignard carbonyl)
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Bromfenac
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