Weight | 317.476 g/mol |
---|---|
Formula | C23H27N |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 0 |
Aromatic Rings | 3 |
Rotatable Bonds | 4 |
butenafine (101828-21-1)
Mentax · butenafine hydrochloride · N-4-tert-butylbenzyl-N-methyl-1-naphthalene methylamine hydrochloride
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- Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream (Tropical Medicine & International Health, 1999)
- Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs. (Antimicrobial Agents and Chemotherapy, 1990)
- Anti-Trichophyton mentagrophytes activity and percutaneous permeation of butenafine in guinea pigs (Antimicrobial Agents and Chemotherapy, 1993)
- One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: A multicenter, double-blind trial (Journal of The American Academy of Dermatology, 1997)
- Synthesis and Antifungal Activity of Butenafine Hydrochloride (KP-363), a New Benzylamine Antifungal Agent (Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan, 1991)
- Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria. (International Journal of Dermatology, 2010)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Mentax
- butenafine hydrochloride
- N-4-tert-butylbenzyl-N-methyl-1-naphthalene methylamine hydrochloride
- KP 363
- KP-363
-
SMILESCC(C)(C)C1=CC=C(C=C1)CN(C)CC2=CC=CC3=CC=CC=C32
-
InChIKeyABJKWBDEJIDSJZ-UHFFFAOYSA-N
- Pubchem - butenafine
- Wikipedia - butenafine
Butenafine hydrochloride is a synthetic benzylamine antifungal, marketed under the trade names Mentax, Butop (India) and is the active ingredient in Lotrimin Ultra. It is structurally related to synthetic allylamine antifungals such as terbinafine.
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