Weight | 340.463 g/mol |
---|---|
Formula | C22H28O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
CANRENONE (976-71-6)
Aldadiene · SC 9376 · SC-9376
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- PHARMACOKINETICS OF SPIRONOLACTONE, CANRENONE AND CANRENOATE-K IN HUMANS (Journal of Pharmacology and Experimental Therapeutics, 1973)
- Anti-remodelling effect of canrenone in patients with mild chronic heart failure (AREA IN-CHF study): final results. (European Journal of Heart Failure, 2009)
- Effects of Spironolactone, Canrenone and Canrenoate-K on Cytochrome P450, and 11- and 18-Hydroxylation in Bovine and Human Adrenal Cortical Mitochondria11 (Endocrinology, 1976)
- Digoxin Assays: Frequent, Substantial, and Potentially Dangerous Interference by Spironolactone, Canrenone, and Other Steroids (Clinical Chemistry, 2002)
- Canrenone as a partial agonist at the digitalis receptor site of sodium-potassium-activated adenosine triphosphatase. (Journal of Pharmacology and Experimental Therapeutics, 1981)
- On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro (Naunyn-schmiedebergs Archives of Pharmacology, 1973)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Aldadiene
- SC 9376
- SC-9376
- Phanurane
- 11614 R.P.
- SC9376
-
SMILESCC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C
-
InChIKeyUJVLDDZCTMKXJK-UHFFFAOYSA-N
- Pubchem - CANRENONE
- Wikipedia - canrenone
Canrenone (brand names Contaren, Luvion, Phanurane, Spiroletan) is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium. It is also an important active metabolite of spironolactone, and partially accounts for its therapeutic effects.
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