Weight | 461.817 g/mol |
---|---|
Formula | C21H27Cl3N2O3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 8 |
Cetirizine dihydrochloride (83881-52-1)
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- Sigma-Aldrich - Cetirizine dihydrochloride42.30 - 338.10 USD
- Fisher Scientific - Search for Cetirizine dihydrochloride
- TCI - Cetirizine dihydrochloride82.00 - 283.00 USD
- Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine. (British Journal of Dermatology, 1988)
- Asymmetric synthesis of cetirizine dihydrochloride (Tetrahedron Letters, 2002)
- Spectrophotometric and high performance liquid chromatographic determination of cetirizine dihydrochloride in pharmaceutical tablets (Journal of Pharmaceutical and Biomedical Analysis, 1998)
- Determination of cetirizine dihydrochloride, related impurities and preservatives in oral solution and tablet dosage forms using HPLC. (Journal of Pharmaceutical and Biomedical Analysis, 2004)
- Method development and validation for the simultaneous determination of cetirizine dihydrochloride, paracetamol, and phenylpropanolamine hydrochloride in tablets by capillary zone electrophoresis (Journal of Pharmaceutical and Biomedical Analysis, 2007)
- Screening and RSM optimization for synthesis of a Gum tragacanthacrylic acid based device for in situ controlled cetirizine dihydrochloride release (Soft Matter, 2012)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
-
InChIKeyPGLIUCLTXOYQMV-UHFFFAOYSA-N
- Pubchem - Cetirizine dihydrochloride
- Wikipedia - cetirizine hydrochloride
Cetirizine, sold under the brand name Zyrtec among others, is a potent second-generation antihistamine used in the treatment of hay fever, allergies, angioedema, and urticaria. It acts as a selective antagonist of the histamine H1 receptor. Second-generation antihistamines like cetirizine are less able to cross the bloodbrain barrier and therefore have diminished effects on the central nervous system compared to first-generation drugs.
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