| Weight | 252.361 g/mol |
|---|---|
| Formula | C17H20N2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
1-Benzhydrylpiperazine (841-77-0)
norcyclizine · norcyclizine oxalate (1:2) · norcyclizine oxalate (1:1)
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- Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines (European Journal of Medicinal Chemistry, 2009)
- IMPORTANCE OF TISSUE AND PLASMA BINDING IN DETERMINING THE RETENTION OF NORCHLORCYCLIZINE AND NORCYCLIZINE IN MAN, DOG AND RAT (Journal of Pharmacology and Experimental Therapeutics, 1967)
- New mononuclear organotin(IV) 4-benzhydrylpiperazine-1-carbodithioates : Synthesis, spectroscopic characterization, X-ray structures and in vitro antimicrobial activities (Inorganica Chimica Acta, 2011)
- High-performance liquid chromatographic analysis of cyclizine and its metabolite, norcyclizine in biological fluids using solid phase extraction (Chromatographia, 1987)
- Determination of cyclizine and norcyclizine in plasma and urine using gasliquid chromatography with nitrogen selective detection (Journal of Chromatography B: Biomedical Sciences and Applications, 1981)
- Crystal Structure of a Bioactive Intermediate: 1-Benzhydrylpiperazine (Analytical Sciences: X-ray Structure Analysis Online, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - norcyclizine
- norcyclizine oxalate (1:2)
- norcyclizine oxalate (1:1)
- norcyclizine monohydrochloride
- norcyclizine hydrochloride
-
SMILESC1CN(CCN1)C(C2=CC=CC=C2)C3=CC=CC=C3
-
InChIKeyNWVNXDKZIQLBNM-UHFFFAOYSA-N
- Pubchem - 1-Benzhydrylpiperazine
- Wikipedia - Diphenylmethylpiperazine
1-(Diphenylmethyl)piperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative. It features a piperazine ring with a benzhydryl (diphenylmethyl) group bound to one of the nitrogens.
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Synthesis
benzene
+
Reactant
(Friedel-Crafts alkylation)
Reactant
+
Piperazine
(Chan-Lam coupling reaction)
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