Chlorphentermine hydrochloride (151-06-4)

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Suppliers

• Sigma-Aldrich - Search for Chlorphentermine hydrochloride
• Fisher Scientific - Search for Chlorphentermine hydrochloride
• TCI - Search for Chlorphentermine hydrochloride

Most-cited Publications

• Aminorex, Fenfluramine, and Chlorphentermine Are Serotonin Transporter Substrates Implications for Primary Pulmonary Hypertension (Circulation, 1999)
• Progressive-ratio performance maintained by drug infusions: comparison of cocaine, diethylpropion, chlorphentermine, and fenfluramine. (Psychopharmacology, 1978)
• Chlorphentermine-induced lipidosislike ultrastructural alterations in lungs and adrenal glands of several species. (Toxicology and Applied Pharmacology, 1974)
• Inhibition of the uptake of noradrenaline and 5-hydroxytryptamine by chlorphentermine and chlorimipramine (European Journal of Pharmacology, 1972)
• The ultrastructure of rat lung changes induced by an anorectic drug (Chlorphentermine) (Virchows Archiv B Cell Pathology, 1972)
• A comparative ultrastructural study of the effects of chlorphentermine and triparanol in rat lung and adrenal gland (Virchows Archiv B Cell Pathology, 1972)

Areas of Application

Safety

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Trends

Alternate Names

• Chlorphentermine
• Avipron
• Desopimon
• Pre-Sate
• SMILES
  CC(C)(CC1=CC=C(C=C1)Cl)N.Cl
• InChIKey
  WEJDYJKJPUPMLH-UHFFFAOYSA-N

External Links

• Pubchem - Chlorphentermine hydrochloride
• Wikipedia - chlorphentermine hydrochloride
  Chlorphentermine (trade names Apsedon, Desopimon, Lucofen) is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the 4-chloro derivative of the better known appetite suppressant phentermine, which is still in current use. Chlorphentermine acts as a highly selective serotonin releasing agent (SRA).

Synthesis

CHLOROBENZENE  +  dimethyl-aminoethylchloride (Friedel-Crafts alkylation)

Synthesis of Chlorphentermine hydrochloride ›

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Chlorphentermine hydrochloride

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