| Weight | 276.745 g/mol |
|---|---|
| Formula | C10H13ClN2O3S |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
chlorpropamide (94-20-2)
Diabinese · Glucamide · Clorpropamid
Score:
#1204 in Biology
,
#1380 in Chemistry
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- Letter: Chlorpropamide hypoglycaemia. (The Lancet, 1973)
- Effect of Chlorpropamide on Serum Glucose and Immunoreactive Insulin Concentrations in Patients with Maturity-onset Diabetes Mellitus (Diabetes, 1967)
- Antidiuretic Action of Chlorpropamide in Idiopathic Diabetes Insipidus (The Journal of Clinical Endocrinology and Metabolism, 1966)
- Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. (BMJ, 1978)
- Chlorpropamide hyponatremia: drug-induced inappropriate antidiuretic-hormone activity. (The New England Journal of Medicine, 1971)
- Displacement of tolbutamide, glibenclamide and chlorpropamide from serum albumin by anionic drugs (Biochemical Pharmacology, 1976)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Diabinese
- Glucamide
- Clorpropamid
- Apo-Chlorpropamide
- Insogen
- Meldian
-
SMILESCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)Cl
-
InChIKeyRKWGIWYCVPQPMF-UHFFFAOYSA-N
- Pubchem - chlorpropamide
- Wikipedia - chlorpropamide
Chlorpropamide is a drug in the sulfonylurea class used to treat diabetes mellitus type 2. It is a long-acting first-generation sulfonylurea. It has more side effects than other sulfonylureas and its use is no longer recommended.
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Alternate Names
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Synthesis
Reactant
+
Propylamine
(Schotten-Baumann amide from acid)
Propylboronic acid
+
Reactant
(Chan-Lam coupling reaction)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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chlorpropamide
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