| Weight | 338.772 g/mol |
|---|---|
| Formula | C14H11ClN2O4S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
chlorthalidone (77-36-1)
Hygroton · Thalitone · Chlortalidone
Score:
#1572 in Biology
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#1844 in Chemistry
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- Sigma-Aldrich - chlorthalidone168.00 - 338.10 USD
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- Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) (JAMA, 2000)
- Comparative Antihypertensive Effects of Hydrochlorothiazide and Chlorthalidone on Ambulatory and Office Blood Pressure (Hypertension, 2006)
- Outcomes in Hypertensive Black and Nonblack Patients Treated With Chlorthalidone, Amlodipine, and Lisinopril (JAMA, 2005)
- Hydrochlorothiazide Versus Chlorthalidone Evidence Supporting Their Interchangeability (Hypertension, 2004)
- The Verapamil in Hypertension and Atherosclerosis Study (VHAS): results of long-term randomized treatment with either verapamil or chlorthalidone on carotid intima-media thickness. (Journal of Hypertension, 1998)
- Chlorthalidone reduces calcium oxalate calculous recurrence but magnesium hydroxide does not. (The Journal of Urology, 1988)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Hygroton
- Thalitone
- Chlortalidone
- Oxodoline
- Phthalamudine
- Chlorphthalidolone
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SMILESC1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
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InChIKeyJIVPVXMEBJLZRO-UHFFFAOYSA-N
- Pubchem - chlorthalidone
- Wikipedia - chlorthalidone
Chlortalidone (INN/BAN) or chlorthalidone (USAN) is a diuretic medication used to treat hypertension (high blood pressure), originally marketed as Hygroton in the USA. It is described as a thiazide diuretic (or, rather, a thiazide-like diuretic because it acts similarly to the thiazides but does not contain the benzothiadiazine molecular structure). Compared with other medications of the thiazide class, chlortalidone has the longest duration of action but a similar diuretic effect at maximal therapeutic doses.
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chlorthalidone
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