| Weight | 456.322 g/mol |
|---|---|
| Formula | C21H23Cl2NO6 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
Clevidipine (167221-71-8, 166432-28-6)
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- The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. (Anesthesia & Analgesia, 2008)
- Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients: the results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-1. (Anesthesia & Analgesia, 2007)
- Treatment of Acute Postoperative Hypertension in Cardiac Surgery Patients: An Efficacy Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery-2 (ESCAPE-2), a Randomized, Double-Blind, Placebo-Controlled Trial (Anesthesia & Analgesia, 2008)
- Pharmacodynamic, Pharmacokinetic and Clinical Effects of Clevidipine, an UltrashortActing Calcium Antagonist for Rapid Blood Pressure Control (Cardiovascular Drug Reviews, 2006)
- Clevidipine, an Intravenous Dihydropyridine Calcium Channel Blocker, Is Safe and Effective for the Treatment of Patients With Acute Severe Hypertension (Annals of Emergency Medicine, 2009)
- In vitro hydrolysis rate and protein binding of clevidipine, a new ultrashort-acting calcium antagonist metabolised by esterases, in different animal species and man. (European Journal of Pharmaceutical Sciences, 1999)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCC(=O)OCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
-
InChIKeyKPBZROQVTHLCDU-UHFFFAOYSA-N
- Pubchem - Clevidipine
- Wikipedia - clevidipine
Clevidipine (INN, trade name Cleviprex) is a dihydropyridine calcium channel blocker indicated for the reduction of blood pressure when oral therapy is not feasible or not desirable. It was approved by the United States Food and Drug Administration on August 1, 2008.
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