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  Anesthetic · Anorectic · Antiobesity drug · Cardiac stimulant · Categories by psychoactive drug · Cocaine · Drugs acting on the cardiovascular system · Drugs acting on the gastrointestinal system and metabolism · Drugs acting on the nervous system · Drugs by psychological effect · Euphoriant · Local anesthetic · Monoamine reuptake inhibitor · Otological · Pharmaceutical · Psychoactive drug · Psychoactive drugs by mechanism of action · Psychoanaleptic · Serotonin-norepinephrine-dopamine reuptake inhibitor · Stimulant · Sympathomimetic amine · Vasoconstrictor

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Most-cited Publications

• Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter (Nature, 1996)
• Cocaine receptors on dopamine transporters are related to self-administration of cocaine (Science, 1987)
• The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. (American Journal of Psychiatry, 1985)
• Limbic Activation During Cue-Induced Cocaine Craving (American Journal of Psychiatry, 1999)
• Acute Effects of Cocaine on Human Brain Activity and Emotion (Neuron, 1997)
• Graphical Analysis of Reversible Radioligand Binding from Time-Activity Measurements Applied to (N-11C-methyl)-( -)-Cocaine PET Studies in Human Subjects (Journal of Cerebral Blood Flow and Metabolism, 1990)

Areas of Application

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  Predict GHS Hazards for Any Chemical in silico.
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Trends

Alternate Names

• Cocaine Hydrochloride
• Cocaine HCl
• SMILES
  CN1C2CCC1C(C(C2)OC(=O)C3=CC=CC=C3)C(=O)OC
• InChIKey
  ZPUCINDJVBIVPJ-UHFFFAOYSA-N

External Links

• Pubchem - cocaine
• Wikipedia - cocaine
  Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug. It is commonly snorted, inhaled as smoke, or as a solution injected into a vein. Mental effects may include loss of contact with reality, an intense feeling of happiness, or agitation.

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