| Weight | 346.467 g/mol |
|---|---|
| Formula | C21H30O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
CORTICOSTERONE (50-22-6)
Score:
#659 in Neuroscience
,
#2943 in Biology
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- Two Receptor Systems for Corticosterone in Rat Brain: Microdistribution and Differential Occupation (Endocrinology, 1985)
- Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat (Brain Research, 1972)
- Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid -peptide toxicity in hippocampal neurons (Journal of Neurochemistry, 2002)
- Prenatal Stress Induces High Anxiety and Postnatal Handling Induces Low Anxiety in Adult Offspring: Correlation with Stress-Induced Corticosterone Secretion (The Journal of Neuroscience, 1997)
- Inverted-U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation (Hippocampus, 1992)
- Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone (Proceedings of the National Academy of Sciences of the United States of America, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O
-
InChIKeyOMFXVFTZEKFJBZ-UHFFFAOYSA-N
- Pubchem - CORTICOSTERONE
- Wikipedia - corticosterone
Corticosterone, also known as 17-deoxycortisol and 11,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. It is of minor importance in humans, except in the very rare case of congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency.
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