| Weight | 276.376 g/mol |
|---|---|
| Formula | C17H24O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
cyclandelate (456-59-7)
Cyclospasmol
Score:
#150 in Neurology
,
#668 in Neuroscience
,
#1173 in Biochemistry
,
#2972 in Biology
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- Sigma-Aldrich - cyclandelate128.75 USD
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- Cyclandelate in the prophylaxis of migraine: a randomized, parallel, double-blind study in comparison with placebo and propranolol (Cephalalgia, 1996)
- Effect of cyclandelate on mental function and cerebral blood flow in elderly patients. (BMJ, 1967)
- Clinical efficacy and central mechanisms of cyclandelate in migraine: a double-blind placebo-controlled study. (Functional Neurology, 1998)
- Cyclandelate in the Prophylaxis of Migraine: A Placebo-Controlled Study (Cephalalgia, 2001)
- The Effect of Cyclandelate on Mental Function in Patients with Arteriosclerotic Brain Disease (British Journal of Psychiatry, 1970)
- EFFECT OF CYCLANDELATE ON CEREBRAL CORTEX PERFUSION-RATES IN CEREBROVASCULAR DISEASE (The Lancet, 1966)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cyclospasmol
-
SMILESCC1CC(CC(C1)(C)C)OC(=O)C(C2=CC=CC=C2)O
-
InChIKeyWZHCOOQXZCIUNC-UHFFFAOYSA-N
- Pubchem - cyclandelate
- Wikipedia - cyclandelate
Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.
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Synthesis
Reactant
+
CHLOROBENZENE
(Grignard alcohol)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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cyclandelate
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