| Weight | 337.247 g/mol |
|---|---|
| Formula | C14H10N4NaO5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Dantrium (24868-20-0, 14663-23-1)
Dantrolene · Dantrolene Sodium
Score:
#212 in Neurology
,
#955 in Neuroscience
,
#4176 in Biology
,
#5262 in Chemistry
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- Dantrolene A review of its pharmacology, therapeutic use and new developments (Anaesthesia, 2004)
- Studies on the mechanism of action of dantrolene sodium. A skeletal muscle relaxant. (Naunyn-schmiedebergs Archives of Pharmacology, 1972)
- Dantrolene Prevents Glutamate Cytotoxicity and Ca2+ Release from Intracellular Stores in Cultured Cerebral Cortical Neurons (Journal of Neurochemistry, 1991)
- Calcium release from skeletal muscle sarcoplasmic reticulum: site of action of dantrolene sodium (Science, 1976)
- In vitro antioxidant properties of dantrolene sodium. (Pharmacological Research, 2001)
- Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia (Embo Molecular Medicine, 2012)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dantrolene
- Dantrolene Sodium
-
SMILESC1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-].[Na]
-
InChIKeyBDZCLIOURDFSFQ-UHFFFAOYSA-N
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Synthesis
Reactant
+
4-Chloronitrobenzene
(Suzuki)
Reactant
+
4-Chloronitrobenzene
(Decarboxylative coupling)
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