| Weight | 139.154 g/mol |
|---|---|
| Formula | C7H9NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
deferiprone (30652-11-0)
CP20 · L1 oral chelate · 3-hydroxy-1,2-dimethyl-4-pyridinone
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#1330 in Biology
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#1547 in Chemistry
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- Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia (The Lancet, 2002)
- Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis (Blood, 2006)
- A Randomized, Placebo-Controlled, Double-Blind Trial of the Effect of Combined Therapy With Deferoxamine and Deferiprone on Myocardial Iron in Thalassemia Major Using Cardiovascular Magnetic Resonance (Circulation, 2007)
- Long-Term Safety and Effectiveness of Iron-Chelation Therapy with Deferiprone for Thalassemia Major (The New England Journal of Medicine, 1998)
- Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemia major (Blood, 2006)
- Iron-chelation therapy with oral deferiprone in patients with thalassemia major (The New England Journal of Medicine, 1995)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - CP20
- L1 oral chelate
- 3-hydroxy-1,2-dimethyl-4-pyridinone
- Hdmpp cpd
- 1,2-dimethyl-3-hydroxypyridin-4-one
- 1,2-dimethyl-3-hydroxypyrid-4-one
- DMOHPO
- Hdpp
- 1,2-dimethyl-3-hydroxy-4-pyridinone
- Ferriprox
-
SMILESCC1=C(C(=O)C=CN1C)O
-
InChIKeyTZXKOCQBRNJULO-UHFFFAOYSA-N
- Pubchem - deferiprone
- Wikipedia - deferiprone
Deferiprone (tradenames include Ferriprox) is a drug that chelates iron and is used to treat iron overload in thalassaemia major. It was first approved for use in treating thalassaemia major in 1994 and had been licensed for use in Europe and Asia for many years while awaiting approval in Canada and the United States. On October 14, 2011, it was approved for use in the US under the FDAs accelerated approval program.
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Synthesis
Similar Compounds
5-hydroxy-1,2-dimethyl-4(1H)-pyridinone
(60403-96-5)
11 alternate names
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3-hydroxy-2-methylquinolin-4(1H)-one
(34497-54-6)
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3-Hydroxy-2-methylpyridine
(1121-25-1)
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1,6-Dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid
(1365963-81-0)
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2-Cyano-3-hydroxypyridine
(932-35-4)
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2,6-Dimethyl-3-hydroxypyridine
(1122-43-6)
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3-Hydroxy-2-pyridinemethanol hydrochloride
(14173-30-9)
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1,2-Dimethylpyridinium iodide
(872-73-1)
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3-hydroxy-6-methyl-2-pyridinecarbaldehyde
(66497-42-5)
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2-methylquinolin-3-ol
(613-19-4)
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2-(Chloromethyl)-3-methoxypyridine hydrochloride
(60617-60-9)
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1,6-dimethyl-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid
(33821-59-9)
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3-Hydroxypyridinium methiodide
(7500-05-2)
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2168-13-0
(2168-13-0)
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2-(hydroxymethyl)-6-methylpyridin-3-ol
(42097-42-7)
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3-methoxy-2-methyl-4-pyridinamine
(1559064-12-8)
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5-Hydroxy-2-methylpyridine
(1121-78-4)
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3 suppliers
3-HYDROXYPICOLINIC ACID
(874-24-8)
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3 suppliers
2-Ethyl-3-hydroxy-6-methylpyridine
(2364-75-2)
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3 suppliers
13258-59-8
(13258-59-8)
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3-Hydroxypicolinamide
(933-90-4)
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4-CHLORO-3-METHOXY-2-METHYLPYRIDINE
(107512-34-5)
11 alternate names
3 suppliers
5-hydroxypicolinaldehyde
(31191-08-9)
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3 suppliers
(2-methyl-4-oxo-1(4H)-quinolinyl)acetic acid
(946666-39-3)
11 alternate names
3 suppliers
1,2-dimethyl-1H-indol-5-ol
(25888-06-6)
11 alternate names
3 suppliers
2-(2-phenylethyl)pyridin-3-ol
(154538-13-3)
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3 suppliers
6-(hydroxymethyl)pyridin-3-ol
(40222-77-3)
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3 suppliers
2-Amino-6-methylpyridin-3-ol
(20348-16-7)
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mexidol
(127464-43-1)
11 alternate names
3 suppliers
62733-99-7
(62733-99-7)
11 alternate names
3 suppliers
4-Bromo-5-methoxy-2-methylpyridine
(1256804-48-4)
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3 suppliers
1-(3-aminopropyl)-6-methyl-2(1H)-pyridinone dihydrochloride
(1609403-57-7)
11 alternate names
3 suppliers
4-Deoxypyridoxine hydrochloride
(148-51-6)
11 alternate names
3 suppliers
6-methyl-4-oxo-1,4-dihydro-2-pyridinecarboxylic acid
(14255-41-5)
11 alternate names
3 suppliers
6,8-dibromo-2-methylquinolin-3-ol
(59869-01-1)
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3 suppliers
CHELIDAMIC ACID
(138-60-3)
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3 suppliers
4-Bromo-2-methylquinolin-3-ol
(13235-12-6)
11 alternate names
3 suppliers
3-Hydroxy-4-methoxypyridine-2-carboxylic acid
(210300-09-7)
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3 suppliers
xanthurenic acid
(59-00-7)
11 alternate names
3 suppliers
2-bromo-3-methoxy-6-methylpyridine
(24207-22-5)
11 alternate names
3 suppliers
3-Hydroxy-2-iodo-6-methylpyridine
(23003-30-7)
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3 suppliers
4-Hydroxy-2-methylquinoline
(607-67-0)
11 alternate names
3 suppliers
PYRIDOXINE HYDROCHLORIDE
(8059-24-3, 58-56-0, 8064-77-5)
11 alternate names
3 suppliers
5-Methoxy-1-methyl-1H-indole-2-carboxylic acid
(59908-54-2)
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3 suppliers
1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-6-carboxylic acid hydrate
(1559059-89-0)
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3 suppliers
1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-6-carboxylic acid
(5368-42-3)
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1,2-DIMETHYLINDOLE
(875-79-6)
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PYRIDOXAL HYDROCHLORIDE
(65-22-5)
11 alternate names
3 suppliers
[(2-ethyl-6-methyl-3-pyridinyl)oxy]acetic acid hydrochloride
(125756-86-7)
11 alternate names
3 suppliers
1-Methyl-1H-indole-2-carbaldehyde
(27421-51-8)
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3 suppliers
6-Methoxy-1-methyl-1H-indole-2-carboxylic acid
(739365-07-2)
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1,5-dimethyl-1H-indole-2-carbaldehyde
(883526-76-9)
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3 suppliers
8-Hydroxyquinaldine
(826-81-3)
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3 suppliers
PYRIDOXAMINE DIHYDROCHLORIDE
(524-36-7)
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3 suppliers
1,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid
(889939-62-2)
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3 suppliers
2-(chloromethyl)-4(1H)-quinolinone
(946712-03-4)
11 alternate names
3 suppliers
(1-methyl-1H-indol-2-yl)methanol
(1485-22-9)
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3 suppliers
6-Chloro-5-methoxypicolinic acid
(112750-30-8)
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1-Ethyl-2-methyl-1H-indole
(40876-94-6)
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3 suppliers
3-(6-methyl-2-oxo-1(2H)-pyridinyl)propanoic acid
(859296-04-1)
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4-Methoxypicolinic acid
(29082-91-5)
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8-Hydroxyquinoline-2-carboxaldehyde
(14510-06-6)
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1-Methyl-1H-indole-2-carboxylic acid
(16136-58-6)
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3 suppliers
2-(chloromethyl)-3,5-dimethylpyridin-4(1H)-one hydrochloride
(220770-99-0)
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1,4,6-trimethyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile
(64038-03-5)
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6-Fluoro-2-methylquinolin-4-ol
(15912-68-2)
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5-fluoro-1-methyl-1H-indole-2-carbaldehyde
(883531-48-4)
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3-Hydroxy-6-methyl-2-nitropyridine
(15128-90-2)
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8-Methoxy-2-methylquinoline
(3033-80-5)
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1,5-Dimethyl-1H-indole-2-carboxylic acid
(216210-59-2)
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8-hydroxyquinoline-2-carboxylic acid
(1571-30-8)
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117-57-7
(117-57-7)
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5-Hydroxy-2-methylisonicotinic acid
(27951-89-9)
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6-Methoxyquinaldine
(1078-28-0)
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1,2-DIMETHYL-1H-INDOL-5-AMINE HYDROCHLORIDE
(174274-98-7)
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2-(2-METHYL-1H-INDOL-1-YL)ETHANAMINE
(883535-89-5)
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41468-25-1
(41468-25-1)
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8-methoxyquinoline-2-carbaldehyde
(103854-64-4)
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3 suppliers
2-(aminomethyl)-3,5-dimethyl-4(1H)-pyridinone dihydrochloride hydrate
(1114596-81-4)
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3 suppliers
4-Hydroxy-6-methylnicotinic acid
(33821-58-8)
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3 suppliers
2-heptylquinolin-4(1H)-one
(2503-80-2)
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Conductase
(27280-85-9)
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2-(2-methyl-1H-indol-1-yl)ethanamine sulfate
(1185568-62-0)
11 alternate names
3 suppliers
distigmine bromide
(15876-67-2)
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3 suppliers
(4-Methoxypyridin-2-yl)methanamine
(194658-14-5)
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3 suppliers
1,4,6-trimethyl-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid
(24667-08-1)
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3 suppliers
1,6-dimethyl-1H-indole-2-carboxylic acid
(893730-44-4)
11 alternate names
3 suppliers
6-chloro-1-methyl-1H-indole-2-carboxylic acid
(680569-83-9)
11 alternate names
3 suppliers
5-Fluoro-1-methyl-1H-indole-2-carboxylic acid
(167631-50-7)
11 alternate names
3 suppliers
1-ethyl-6-methyl-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid
(1119446-11-5)
11 alternate names
3 suppliers
2-methylquinolin-6-ol
(613-21-8)
11 alternate names
3 suppliers
2-(chloromethyl)-6-fluoro-4(1H)-quinolinone
(946712-15-8)
11 alternate names
3 suppliers
1,7-dimethyl-1H-indole-2-carboxylic acid
(858233-18-8)
11 alternate names
3 suppliers
2-(chloromethyl)-6-methyl-4(1H)-quinolinone
(946755-45-9)
11 alternate names
3 suppliers
Chlorquinaldol
(72-80-0)
11 alternate names
3 suppliers
2-(chloromethyl)-4-methoxypyridine hydrochloride
(62734-08-1)
11 alternate names
3 suppliers
deferiprone
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