Score: #205 in Neurology , #909 in Neuroscience , #1846 in Biochemistry , #3992 in Biology

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Suppliers

• Sigma-Aldrich - DEXTRORPHAN
  512.00 - 921.00 USD
• Fisher Scientific - Search for DEXTRORPHAN
• TCI - Search for DEXTRORPHAN

Most-cited Publications

• Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy (Brain Research, 1993)
• Safety, Tolerability, and Pharmacokinetics of the N-Methyl-d-Aspartate Antagonist Dextrorphan in Patients With Acute Stroke (Stroke, 1995)
• Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity (Brain Research, 1987)
• Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons. (Journal of Pharmacology and Experimental Therapeutics, 1987)
• Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids. (European Journal of Pharmacology, 1985)
• Dextrorphan relieves neuropathic heat-evoked hyperalgesia in the rat (Neuroscience Letters, 1993)

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Alternate Names

• (+-)-17-Methylmorphinan-3-ol
• SMILES
  CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O
• InChIKey
  JAQUASYNZVUNQP-UHFFFAOYSA-N

External Links

• Pubchem - DEXTRORPHAN
• Wikipedia - dextrorphan
  Dextrorphan (DXO) is a psychoactive drug of the morphinan class which acts as an antitussive or cough suppressant and dissociative hallucinogen. It is the dextrorotatory-stereoisomer of racemorphan, the levo-half being levorphanol. Dextrorphan is produced by O-demethylation of dextromethorphan by CYP2D6.

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