| Weight | 297.354 g/mol |
|---|---|
| Formula | C18H19NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
Oripavine (467-04-9)
O(3)-dimethylthebaine · 6-demethoxythebaine · oripavine hydrochloride, (5alpha)-isomer
Score:
#884 in Biochemistry
,
#2359 in Biology
,
#2923 in Chemistry
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- THE ANIMAL PHARMACOLOGY OF BUPRENORPHINE, AN ORIPAVINE ANALGESIC AGENT (British Journal of Pharmacology, 1977)
- Transformation of thebaine to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes. (Proceedings of the National Academy of Sciences of the United States of America, 1988)
- Ring C-bridged derivatives of thebaine and oripavine. (Advances in biochemical psychopharmacology, 1973)
- Determination of morphine, oripavine and pseudomorphine using capillary electrophoresis with acidic potassium permanganate chemiluminescence detection (Analyst, 2000)
- 6-Demethoxythebaine and its conversion to analgesics of the 6,14-ethenomorphinan type (Journal of Medicinal Chemistry, 1981)
- Synthesis of thebaine and oripavine from codeine and morphine (Journal of Medicinal Chemistry, 1975)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - O(3)-dimethylthebaine
- 6-demethoxythebaine
- oripavine hydrochloride, (5alpha)-isomer
-
SMILESCN1CCC23C4C(=CC=C2C1CC5=C3C(=C(C=C5)O)O4)OC
-
InChIKeyZKLXUUYLEHCAMF-UHFFFAOYSA-N
- Pubchem - Oripavine
- Wikipedia - oripavine
Oripavine is an opiate and the major metabolite of thebaine. It is the parent compound from which a series of semi-synthetic opioids are derived, which includes the compounds etorphine and buprenorphine. Although its analgesic potency is comparable to morphine, it is not used clinically due to its severe toxicity and low therapeutic index.
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