Weight | 337.803 g/mol |
---|---|
Formula | C17H20ClNO4 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
Oxymorphone HCl (357-07-3)
Oxymorphone · Numorphan · Opana
Score:
#13 in Medicinal chemistry
,
#3585 in Chemistry
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- Efficacy and safety of OPANA ER (oxymorphone extended release) for relief of moderate to severe chronic low back pain in opioid-experienced patients: a 12-week, randomized, double-blind, placebo-controlled study. (The Journal of Pain, 2007)
- Efficacy and safety of oxymorphone extended release in chronic low back pain: Results of a randomized, double-blind, placebo- and active-controlled phase III study (The Journal of Pain, 2005)
- Community Outbreak of HIV Infection Linked to Injection Drug Use of Oxymorphone--Indiana, 2015. (Morbidity and Mortality Weekly Report, 2015)
- A 12-week, randomized, placebo-controlled trial assessing the safety and efficacy of oxymorphone extended release for opioid-naive patients with chronic low back pain (Current Medical Research and Opinion, 2007)
- Comparison of Histamine Release in Human Skin Mast Cells Induced by Morphine, Fentanyl, and Oxymorphone (Anesthesiology, 1984)
- Oxymorphone ExtendedRelease Tablets Relieve Moderate to Severe Pain and Improve Physical Function in Osteoarthritis: Results of a Randomized, DoubleBlind, Placebo and ActiveControlled Phase III Trial (Pain Medicine, 2005)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Oxymorphone
- Numorphan
- Opana
- Oxymorphone Hydrochloride
- Bristol-Myers Squibb Brand of Oxymorphone Hydrochloride
- Endo brand of oxymorphine HCl
- Endo Brand of Oxymorphone Hydrochloride
-
SMILESCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
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InChIKeyBCGJBQBWUGVESK-UHFFFAOYSA-N
- Pubchem - Oxymorphone HCl
- Wikipedia - oxymorphone hydrochloride
Oxymorphone, sold under the brand names Numorphan among others, is a powerful semi-synthetic opioid analgesic (painkiller) developed in Germany in 1914. Pain relief after injection begins after about 510 minutes and 1530 minutes after rectal administration, and lasts about 34 hours for immediate-release tablets and 12 hours for extended-release tablets. It is highly addictive and in June 2017 the FDA asked the manufacturer to remove its product from the US market.
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