protopine (130-86-9)

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  10 mg
  $350.00

Most-cited Publications

• Elicitor induction and characterization of microsomal protopine-6-hydroxylase, the central enzyme in benzophenanthridine alkaloid biosynthesis. (Phytochemistry, 1990)
• Solidliquid extraction of protopine from Fumaria officinalis L.Analysis determination, kinetic reaction and model building (Separation and Purification Technology, 2007)
• Protective effects of protopine on hydrogen peroxide-induced oxidative injury of PC12 cells via Ca2+ antagonism and antioxidant mechanisms (European Journal of Pharmacology, 2008)
• ANTI-THROMBOTIC AND ANTI-INFLAMMATORY ACTIVITIES OF PROTOPINE (Pharmacological Research, 1997)
• Protopine from Corydalis ternata has anticholinesterase and antiamnesic activities. (Planta Medica, 1999)
• Simultaneous determination of tetrahydropalmatine, protopine, and palmatine in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study (Journal of Pharmaceutical and Biomedical Analysis, 2009)

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Trends

Alternate Names

• fumarine
• protopine mesylate
• 4,6,7,14-tetrahydro-5-methyl-bis(1,3)benzodioxolo(4,5-c-5',6'-g)azecin-13(5H)-one
• protopine hydrochloride
• SMILES
  CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3
• InChIKey
  GPTFURBXHJWNHR-UHFFFAOYSA-N

External Links

• Pubchem - protopine
• Wikipedia - protopine
  Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.

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protopine

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