Weight | 415.961 g/mol |
---|---|
Formula | C24H30ClNO3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 6 |
Donepezil hydrochloride (120011-70-3)
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- Donepezil Hydrochloride (E2020) and Other Acetylcholinesterase Inhibitors (Current Medicinal Chemistry, 2000)
- A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement (International Journal of Geriatric Psychiatry, 2007)
- Research and development of donepezil hydrochloride, a new type of acetylcholinesterase inhibitor. (Japanese Journal of Pharmacology, 2002)
- Donepezil Hydrochloride Preserves Regional Cerebral Blood Flow in Patients with Alzheimers Disease (The Journal of Nuclear Medicine, 2001)
- A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments (Journal of Clinical Psychopharmacology, 2000)
- Effect of donepezil hydrochloride (E2020) on basal concentration of extracellular acetylcholine in the hippocampus of rats (European Journal of Pharmacology, 1999)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCOC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
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InChIKeyXWAIAVWHZJNZQQ-UHFFFAOYSA-N
- Pubchem - Donepezil hydrochloride
- Wikipedia - donepezil hydrochloride
Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease. Donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease. Common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping.
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