| Weight | 293.407 g/mol |
|---|---|
| Formula | C17H27NO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 10 |
NONIVAMIDE (2444-46-4)
N-vanillylnonanamide · vanillyl-N-nonylamide · vanillylnonanamide
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- In vitro and in vivo evaluations of topically applied capsaicin and nonivamide from hydrogels. (International Journal of Pharmaceutics, 2001)
- Transdermal delivery of capsaicin derivative-sodium nonivamide acetate using microemulsions as vehicles. (International Journal of Pharmaceutics, 2008)
- Determination of capsaicin, dihydrocapsaicin, and nonivamide in self-defense weapons by liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry (Journal of Chromatography A, 2001)
- Nonivamide, a Constituent of Capsicum oleoresin (Journal of Natural Products, 1996)
- Transdermal iontophoresis of sodium nonivamide acetate. V. Combined effect of physical enhancement methods. (International Journal of Pharmaceutics, 2002)
- In vitro topical application and in vivo pharmacodynamic evaluation of nonivamide hydrogels using Wistar rat as an animal model (European Journal of Pharmaceutical Sciences, 2002)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - N-vanillylnonanamide
- vanillyl-N-nonylamide
- vanillylnonanamide
-
SMILESCCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
-
InChIKeyRGOVYLWUIBMPGK-UHFFFAOYSA-N
- Pubchem - NONIVAMIDE
- Wikipedia - nonivamide
Nonivamide, also called pelargonic acid vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of pelargonic acid (n-nonanoic acid) and vanillyl amine. It is present in chili peppers, but is commonly manufactured synthetically.
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Synthesis
Reactant
+
Methyl hydroperoxide
(Dakin oxidation)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
Nonanamide
+
Reactant
(Alkylation of primary amines)
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NONIVAMIDE
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