Weight | 466.018 g/mol |
---|---|
Formula | C25H36ClNO5 |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 13 |
MEBEVERINE HYDROCHLORIDE (2753-45-9)
mebeverine · 4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate · spasmotalin
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- Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients (Alimentary Pharmacology & Therapeutics, 1999)
- Comparison of the therapeutic effect of wheat bran, mebeverine and placebo in patients with the irritable bowel syndrome. (Digestion, 1986)
- Physiological and clinical assessment of the effect of the musculotropic agent mebeverine on the human colon. (BMJ, 1965)
- Application of first-derivative UV-spectrophotometry, TLC-densitometry and liquid chromatography for the simultaneous determination of mebeverine hydrochloride and sulpiride (Journal of Pharmaceutical and Biomedical Analysis, 1999)
- DEVELOPMENT OF IN SITU GELLING AND MUCOADHESIVE MEBEVERINE HYDROCHLORIDE SOLUTION FOR RECTAL ADMINISTRATION (2003)
- A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome (World Journal of Gastroenterology, 2010)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - mebeverine
- 4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate
- spasmotalin
- duspatalin
-
SMILESCCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC.Cl
-
InChIKeyPLGQWYOULXPJRE-UHFFFAOYSA-N
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Synthesis
3,4-Dimethoxybenzoic acid
+
Reactant
(Ester from carboxilic acid(SN2))
ANISOLE
+
Reactant
(Friedel-Crafts alkylation)
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