| Weight | 300.398 g/mol |
|---|---|
| Formula | C19H24O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
2-METHOXYESTRONE (362-08-3)
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- 2-Methoxyestrone, a new metabolite of estradiol-17 beta in man. (Journal of Biological Chemistry, 1957)
- pKa values of estrone, 17-estradiol and 2-methoxyestrone (Steroids, 1979)
- 2-Methoxyestrone, A Metabolite of Estradiol-17 in the Human1 (Journal of the American Chemical Society, 1957)
- Radioimmunoassay of 2-hydroxyestrone and 2-methoxyestrone in human urine (Steroids, 1979)
- Metabolism of 2-Methoxyestrone in Normal Men* (The Journal of Clinical Endocrinology and Metabolism, 1983)
- Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate. (Molecular and Cellular Endocrinology, 2000)
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SMILESCC12CCC3C(C1CCC2=O)CCC4=CC(=C(C=C34)OC)O
-
InChIKeyWHEUWNKSCXYKBU-UHFFFAOYSA-N
- Pubchem - 2-METHOXYESTRONE
- Wikipedia - 2-methoxyestrone
2-Methoxyestrone (2-ME1) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estrone that is formed by catechol O-methyltransferase via the intermediate 2-hydroxyestrone. Unlike estrone but similarly to 2-hydroxyestrone and 2-methoxyestradiol, 2-methoxyestrone has very low affinity for the estrogen receptor and lacks significant estrogenic activity.
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