| Weight | 332.484 g/mol |
|---|---|
| Formula | C21H32O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
21-Hydroxypregnenolone (1164-98-3)
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- Role of 21-hydroxypregnenolone and of 17-, 21-dihydroxypregnenolone in the biogenesis of C21 and C19 steroids by adrenal gland slices (Steroids, 1964)
- Role of 21-hydroxypregnenolone in the synthesis of corticosterone from pregnenolone by sheep adrenal tissue in vitro (General and Comparative Endocrinology, 1967)
- Steroid 21-hydroxylation by human preovulatory follicles from stimulated cycles: A mass spectrometrical study of deoxycorticosterone, 21-hydroxypregnenolone and 11-deoxycortisol in follicular fluid (Journal of Steroid Biochemistry, 1987)
- STUDIES ON THE METABOLISM OF C-21 STEROIDS IN THE HUMAN FOETO-PLACENTAL UNIT. I. FORMATION OF A BETA-UNSATURATED 3-KETONES IN MIDTERM PLACENTAS PERFUSED IN SITU WITH PREGNENOLONE AND 17-ALPHA-HYDROXYPREGNENOLONE. (European Journal of Endocrinology, 1965)
- Studies on the metabolism of corticosteroids in the human foeto-placental unit. 3. Role of 21-hydroxypregnenolone in the biosynthesis of corticosteroids. (European Journal of Endocrinology, 1970)
- A paradox: elevated 21-hydroxypregnenolone production in newborns with 21-hydroxylase deficiency (Steroids, 1987)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC12CCC3C(C1CCC2C(=O)CO)CC=C4C3(CCC(C4)O)C
-
InChIKeyMOIQRAOBRXUWGN-UHFFFAOYSA-N
- Pubchem - 21-Hydroxypregnenolone
- Wikipedia - 21-hydroxypregnenolone
21-Hydroxypregnenolone, also known as prebediolone, as well as 3,21-dihydroxypregn-5-en-20-one, is a naturally occurring, endogenous pregnane steroid and an intermediate in the biosynthesis of 11-deoxycorticosterone (21-hydroxyprogesterone), corticosterone (11,21-dihydroxyprogesterone), and other corticosteroids. It is formed from pregnenolone in the adrenal glands. The 21-acetate ester of 21-hydroxypregnenolone, prebediolone acetate, is described as a glucocorticoid and has been used in the treatment of rheumatoid arthritis.
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