| Weight | 384.648 g/mol |
|---|---|
| Formula | C27H44O |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
DESMOSTEROL (313-04-2)
24 Dehydrocholesterol · 24-Dehydrocholesterol · Demosterol
Score:
#1491 in Biochemistry
,
#3499 in Biology
,
#4376 in Chemistry
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- Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses (Cell, 2012)
- Studies of cholesterol biosynthesis. I. The identification of desmosterol in serum and tissues of animals and man treated with MER-29. (Journal of Biological Chemistry, 1960)
- ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain (The FASEB Journal, 2007)
- Unique lipids of primate spermatozoa: desmosterol and docosahexaenoic acid. (Journal of Lipid Research, 1993)
- Uneven distribution of desmosterol and docosahexaenoic acid in the heads and tails of monkey sperm (Journal of Lipid Research, 1998)
- Significance of Sterol Structural Specificity DESMOSTEROL CANNOT REPLACE CHOLESTEROL IN LIPID RAFTS (Journal of Biological Chemistry, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 24 Dehydrocholesterol
- 24-Dehydrocholesterol
- Demosterol
-
SMILESCC(CCC=C(C)C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
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InChIKeyAVSXSVCZWQODGV-UHFFFAOYSA-N
- Pubchem - DESMOSTEROL
- Wikipedia - desmosterol
Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. 24-dehydrocholesterol reductase catalyses the reduction of desmosterol to cholesterol.
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