| Weight | 376.581 g/mol |
|---|---|
| Formula | C24H40O3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
LITHOCHOLIC ACID (434-13-9)
Lithocholate · Isolithocholic Acid
Score:
#1056 in Biochemistry
,
#1207 in Physics
,
#3434 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - LITHOCHOLIC ACID49.00 - 168.00 USD
- Fisher Scientific - Search for LITHOCHOLIC ACID
- TCI - Search for LITHOCHOLIC ACID
- The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity (Proceedings of the National Academy of Sciences of the United States of America, 2001)
- Bile acid sulfates. I. Synthesis of lithocholic acid sulfates and their identification in human bile. (Journal of Lipid Research, 1971)
- Detoxification of Lithocholic Acid, A Toxic Bile Acid: Relevance to Drug Hepatotoxicity (Drug Metabolism Reviews, 2004)
- Metabolism of lethocholate in healthy man. I. Biotransformation and biliary excretion of intravenously administered lithocholate, lithocholylglycine, and their sulfates. (Gastroenterology, 1975)
- Lithocholic Acid Decreases Expression of Bile Salt Export Pump through Farnesoid X Receptor Antagonist Activity (Journal of Biological Chemistry, 2002)
- Pathogenesis of lithocholate- and taurolithocholate-induced intrahepatic cholestasis in rats. (Gastroenterology, 1978)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Lithocholate
- Isolithocholic Acid
-
SMILESCC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
-
InChIKeySMEROWZSTRWXGI-UHFFFAOYSA-N
- Pubchem - LITHOCHOLIC ACID
- Wikipedia - lithocholic acid
Lithocholic acid, also known as 3-hydroxy-5-cholan-24-oic acid or LCA, is a bile acid that acts as a detergent to solubilize fats for absorption. Bacterial action in the colon produces LCA from chenodeoxycholic acid by reduction of the hydroxyl functional group at carbon-7 in the "B" ring of the steroid framework. It has been implicated in human and experimental animal carcinogenesis.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Similar Compounds
Isolithocholic acid
(1534-35-6)
3 alternate names
3 suppliers
DESMOSTEROL
(313-04-2)
3 alternate names
3 suppliers
Dihydrocholesterol
(80-97-7)
3 alternate names
3 suppliers
Zymosterol
(128-33-6)
3 alternate names
3 suppliers
Lathosterol
(80-99-9)
3 alternate names
3 suppliers
Glycolithocholic acid
(474-74-8)
3 alternate names
3 suppliers
3,7-Dihydroxy-12-oxocholanoic acid
(2458-08-4)
3 alternate names
3 suppliers
7-Ketodeoxycholic acid
(911-40-0)
3 alternate names
3 suppliers
Zymostenol
(566-97-2)
3 alternate names
3 suppliers
estradiol valerate
(979-32-8)
3 alternate names
3 suppliers
7-Dehydrocholesterol
(434-16-2)
3 alternate names
3 suppliers
27-hydroxycholesterol
(20380-11-4)
3 alternate names
3 suppliers
Cerebrosterol
(474-73-7)
3 alternate names
3 suppliers
22R-hydroxycholesterol
(22348-64-7, 17954-98-2)
3 alternate names
3 suppliers
17-Hydroxypregnenolone
(387-79-1)
3 alternate names
3 suppliers
4,4-Dimechol-8,14,24-trienol
(64284-64-6)
3 alternate names
3 suppliers
Coprocholic acid
(547-98-8)
3 alternate names
3 suppliers
BETA-SITOSTEROL
(68555-08-8, 19044-06-5, 83-46-5)
3 alternate names
3 suppliers
STIGMASTEROL
(83-48-7)
3 alternate names
3 suppliers
testosterone enanthate
(315-37-7)
3 alternate names
3 suppliers
Glycocholic acid
(475-31-0)
3 alternate names
3 suppliers
Norethindrone acetate
(38673-38-0, 51-98-9)
3 alternate names
3 suppliers
19-Norethindrone acetate
(51-98-9)
3 alternate names
3 suppliers
Deoxycorticosterone acetate
(56-47-3)
3 alternate names
3 suppliers
4-Cholesten-3-one
(601-57-0)
3 alternate names
3 suppliers
hydroxyprogesterone
(604-09-1, 68-96-2)
3 alternate names
3 suppliers
hydrocortisone acetate
(50-03-3)
3 alternate names
3 suppliers
17alpha-Hydroxypregn-4-ene-3,20-dione
(604-09-1)
3 alternate names
3 suppliers
Testosterone undecanoate
(5949-44-0)
3 alternate names
3 suppliers
7alpha-Hydroxy-4-cholesten-3-one
(3862-25-7)
3 alternate names
3 suppliers
21-Deoxyhydrocortisone
(641-77-0)
3 alternate names
3 suppliers
LITHOCHOLIC ACID
CAS Directory
