| Weight | 332.484 g/mol |
|---|---|
| Formula | C21H32O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
17-Hydroxypregnenolone (387-79-1)
Hydroxypregnenolone · 17-Hydroxypregnenolone, (3beta,13alpha,17alpha)-Isomer · 17-Hydroxypregnenolone, (3alpha)-Isomer
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- Radioimmunoassay of Plasma Pregnenolone, 17-Hydroxypregnenolone and Dehydroepiandrosterone Under Various Physiological Conditions (The Journal of Clinical Endocrinology and Metabolism, 1973)
- 7-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system (Proceedings of the National Academy of Sciences of the United States of America, 2004)
- EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES. II. IN VITRO CONVERSION OF PREGNENOLONE-3H SULFATE-35S TO 17ALPHA-HYDROXYPREGNENOLONE-3H SULFATE-35S. (Biochemistry, 1964)
- 7-Hydroxypregnenolone Mediates Melatonin Action Underlying Diurnal Locomotor Rhythms (The Journal of Neuroscience, 2008)
- Simultaneous determination of 17-hydroxypregnenolone and 17-hydroxyprogesterone in dried blood spots from low birth weight infants using LCMS/MS (Journal of Pharmaceutical and Biomedical Analysis, 2008)
- Prolactin Increases the Synthesis of 7-Hydroxypregnenolone, a Key Factor for Induction of Locomotor Activity, in Breeding Male Newts (Endocrinology, 2010)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Hydroxypregnenolone
- 17-Hydroxypregnenolone, (3beta,13alpha,17alpha)-Isomer
- 17-Hydroxypregnenolone, (3alpha)-Isomer
- 17alpha-Hydroxypregnenolone
- 17 alpha Hydroxypregnenolone
- 17 alpha-Hydroxypregnenolone
- 17-Hydroxypregnenolone, (3beta,17alpha)-Isomer
- 17-Hydroxypregnenolone, (3beta,13alpha)-Isomer
- 17alpha Hydroxypregnenolone
- 17 Hydroxypregnenolone
- 17-alpha-Hydroxypregnenolone
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SMILESCC(=O)C1(CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)O
-
InChIKeyJERGUCIJOXJXHF-UHFFFAOYSA-N
- Pubchem - 17-Hydroxypregnenolone
- Wikipedia - 17-Hydroxypregnenolone
17-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17 position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline.
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