Weight | 348.527 g/mol |
---|---|
Formula | C22H36O3 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 15 |
ANACARDIC ACID (16611-84-0, 11034-77-8)
Score:
#1765 in Biochemistry
,
#3878 in Biology
,
#4884 in Chemistry
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- Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-Bregulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-B kinase, leading to potentiation of apoptosis (Blood, 2008)
- Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation (FEBS Letters, 2006)
- ANTIBACTERIAL ACTIVITY OF ANACARDIC ACID AND TOTAROL, ALONE AND IN COMBINATION WITH METHICILLIN, AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (Journal of Applied Microbiology, 1996)
- Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression during In Vitro Plasmodium falciparum Development (Eukaryotic Cell, 2008)
- Emerging roles of anacardic acid and its derivatives: a pharmacological overview. (Basic & Clinical Pharmacology & Toxicology, 2012)
- Expression of a delta 9 14:0-acyl carrier protein fatty acid desaturase gene is necessary for the production of omega 5 anacardic acids found in pest-resistant geranium (Pelargonium xhortorum). (Proceedings of the National Academy of Sciences of the United States of America, 1996)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCCCCCCCCCCCCCC1=C(C(=CC=C1)O)C(=O)O
-
InChIKeyADFWQBGTDJIESE-UHFFFAOYSA-N
- Pubchem - ANACARDIC ACID
- Wikipedia - Anacardic acid
Anacardic acids are phenolic lipids, chemical compounds found in the shell of the cashew nut (Anacardium occidentale). An acid form of urushiol, they also cause an allergic skin rash on contact, known as urushiol-induced contact dermatitis. Anacardic acid is a yellow liquid.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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