| Weight | 309.409 g/mol |
|---|---|
| Formula | C20H23NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
Dioxadrol (6495-46-1)
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- Inhibition of carbachol-induced inositol phosphate accumulation by phencyclidine, phencyclidine-like ligands and sigma agonists involves blockade of the muscarinic cholinergic receptor: a novel dioxadrol-preferring interaction. (Journal of Pharmacology and Experimental Therapeutics, 1990)
- Phencyclidine-like discriminative stimulus properties of the stereoisomers of dioxadrol. (1984)
- Synthesis and NMDA receptor affinity of fluorinated dioxadrol analogues (Bioorganic & Medicinal Chemistry, 2010)
- Evidence for separation of anesthetic activity from prototypic phencyclidine action in drug discrimination by molecular modification of dioxadrol, a phencyclidine-like dissociative anesthetic. (NIDA research monograph, 1984)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1CCNC(C1)C2COC(O2)(C3=CC=CC=C3)C4=CC=CC=C4
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InChIKeyHGKAMARNFGKMLC-UHFFFAOYSA-N
- Pubchem - Dioxadrol
- Wikipedia - dioxadrol
Dexoxadrol (Dioxadrol) is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. Dexoxadrol, along with another related drug etoxadrol, were developed as analgesics for use in humans, but development was discontinued after patients reported side effects such as nightmares and hallucinations.
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