Weight | 333.884 g/mol |
---|---|
Formula | C18H20ClNOS |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 6 |
DULOXETINE HYDROCHLORIDE (136434-34-9)
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- Duloxetine hydrochloride: A new dual-acting medication for the treatment of major depressive disorder (Clinical Therapeutics, 2005)
- An open-label study of duloxetine hydrochloride, a mixed serotonin and noradrenaline reuptake inhibitor, in patients with DSM-III-R major depressive disorder (International Clinical Psychopharmacology, 1997)
- An asymmetric synthesis of duloxetine hydrochloride, a mixed uptake inhibitor of serotonin and norepinephrine, and its C14 labeled isotopomers (Journal of Labelled Compounds and Radiopharmaceuticals, 1995)
- Case Report: Fulminant Hepatic Failure Involving Duloxetine Hydrochloride (Clinical Gastroenterology and Hepatology, 2006)
- Pharmacokinetics of Duloxetine Hydrochloride Enteric-Coated Tablets in Healthy Chinese Volunteers: A Randomized, Open-Label, Single- and Multiple-Dose Study (Clinical Therapeutics, 2009)
- Development and Validation of a Stability-Indicating RP-HPLC Method for Duloxetine Hydrochloride in its Bulk and Tablet Dosage Form (Scientia Pharmaceutica, 2010)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl
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InChIKeyBFFSMCNJSOPUAY-UHFFFAOYSA-N
- Pubchem - DULOXETINE HYDROCHLORIDE
- Wikipedia - duloxetine hydrochloride
Duloxetine, sold under the brand name Cymbalta among others, is a medication mostly used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. It is a thiophene derivative and a selective neurotransmitter reuptake inhibitor for serotonin, norepinephrine, and to a lesser degree dopamine. It belongs to a class of heterocyclic antidepressants known as serotoninnorepinephrine reuptake inhibitors (SNRIs).
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