Weight | 392.908 g/mol |
---|---|
Formula | C19H21ClN2O3S |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 7 |
pioglitazone hydrochloride (112529-15-4)
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- Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: a 6-month randomized placebo-controlled dose-response study. The Pioglitazone 001 Study Group. (Diabetes Care, 2000)
- Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: A randomized, placebo-controlled study (Clinical Therapeutics, 2000)
- Pioglitazone hydrochloride in combination with sulfonylurea therapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, placebo-controlled study (The American Journal of Medicine, 2001)
- Simultaneous Estimation of Metformin Hydrochloride, Pioglitazone Hydrochloride, and Glimepiride by RP-HPLC in Tablet Formulation (Journal of Chromatographic Science, 2008)
- Pioglitazone Hydrochloride Monotherapy Improves Glycemic Control in the Treatment of Patients With Type 2 Diabetes (2000)
- Determination of pioglitazone hydrochloride in bulk and pharmaceutical formulations by HPLC and MEKC methods (Journal of Pharmaceutical and Biomedical Analysis, 2002)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl
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InChIKeyGHUUBYQTCDQWRA-UHFFFAOYSA-N
- Pubchem - pioglitazone hydrochloride
- Wikipedia - pioglitazone hydrochloride
Pioglitazone (brand name Actos) is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results. Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events.
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